Publications

Publications

2020

Obr M, Ricana CL, Nikulin N, Feathers JR, Klanschnig M, Thader A, Johnson MC, Vogt VM, Schur FKM#, Dick RA#
Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
BioRxiv (2020), doi.org/10.1101/2020.12.03.410175

Fäßler F, Dimchev G, Hodirnau VV, Wan W, Schur FKM
Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction
Nature Communications (2020) 11, 6437, doi.org/10.1038/s41467-020-20286-x

Fäßler F*, Zens B*., Hauschild R, Schur FKM
3D printed cell culture grid holders for improved cellular specimen preparation in cryo-electron microscopy
Journal of Structural Biology (2020), 212, 107633, doi.org/10.1016/j.jsb.2020.107633

Hadzijusufovic E, Keller A, Berger A, Greiner G, Wingelhofer B, Witzeneder N, Ivanov D, Pecnard E, Nivarthi H, Schur FKM, Filik Y, Kornauth C, Neubauer HA, Müllauer L, Tin G, Park J, de Araujo ED, Gunning PT, Hoermann G, Gouilleux F, Kralovics R, Moriggl R, Valent P
STAT5 is Expressed in CD34+/CD38− Stem Cells and Serves as a Potential Molecular Target in Ph-Negative Myeloproliferative Neoplasms
Cancers (2020), 12(4), 1021, doi.org/10.3390/cancers12041021

Dick RA*#, Xu C, Morado DR, Kravchuk V, Ricana CL, Lyddon TD, Broad AM, Feathers JR, Johnson MC, Vogt VM, Perilla JR, Briggs JAG, Schur FKM*#
Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly
PLOS Pathogens (2020), 16, e1008277, doi:10.1371/journal.ppat.1008277

2019

Obr M, Schur FKM
Structural Analysis of pleomorphic and asymmetric viruses using cryo-electron tomography and subtomogram averaging
Advances in Virus Research (2019), doi: 10.1016/bs.aivir.2019.07.008

Schur FKM
Toward high-resolution in situ structural biology with cryo-electron tomography and subtomogram averaging
Current Opinion in Structural Biology (2019), 58, 1-9, doi: 10.1016/j.sbi.2019.03.018

2018

Qu K, Glass B, Doležal M, Schur FKM, Murciano B, Rein A, Rumlová M, Ruml T, Kräusslich H-G, Briggs JAG
Structure and architecture of immature and mature murine leukemia virus capsids
PNAS (2018), 115(50), E11751–E11760, doi: 10.1073/pnas.1811580115

Dick RA, Zadrozny KK, Xu C, Schur FKM, Lyddon TD, Ricana CL, Wagner JM, Perilla JR, Ganser-Pornillos BK, Johnson MC, Pornillos O, Vogt VM
Inositol phosphates are assembly co-factors for HIV-1
Nature (2018), 560:509-512. doi: 10.1038/s41586-018-0396-4

2017

Turonova B, Schur FKM, Wan W, Briggs JAG
Efficient 3D-CTF correction for cryo-electron tomography using NovaCTF improves subtomogram averaging resolution to 3.4 Å
Journal of Structural Biology (2017), 199(3); 187-105. doi:10.1016/j.jsb.2017.07.007

2016

Leithner A, Eichner A, Müller J, Reversat A, Brown M, Schwarz J, Merrin J, de Gorter DJ, Schur F, Bayerl J, de Vries I, Wieser S, Hauschild R, Lai FPL, Moser M, Kerjaschki D, Rottner K, Small JV, Stradal TEB, Sixt M
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
Nature Cell Biology (2016), 8(11):1253-1259. doi:10.1038/ncb3426

Schur FKM, Obr M, Hagen WJH, Wan W, Jakobi AJ, Kirkpatrick JM, Sachse C, Kräusslich H-G, Briggs JAG
An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation
Science (2016), 353(6298):506-508. doi: 10.1126/science.aaf9620

Mattei S*, Schur FKM*, Briggs JA
Retrovirus maturation-an extraordinary structural transformation
Current Opinion in Virology (2016) 18, 27-35. doi:10.1016/j.coviro.2016.02.008

Füzik T, Píchalová R, Schur, FKM, Strohalmová K, Křížová I, Hadravová, R, Rumlová M, Briggs JAG, Ulbrich P, Ruml T
Nucleic Acid Binding by Mason–Pfizer Monkey Virus CA Promotes Virus Assembly and Genome Packaging
Journal of Virology (2016) 90(9):4593-603. doi: 10.1128/JVI.03197-15

2015

Schur FKM*, Dick RA*, Hagen WJH, Vogt VM, Briggs JAG.
The structure of the immature-like Rous sarcoma virus Gag particles reveals a structural role for the p10 domain in assembly
Journal of Virology (2015). 89(20):10294-302. doi: 10.1128/JVI.01502-15

Schur FKM, Hagen WJ, Rumlová M, Ruml T, Müller B, Kräusslich HG, Briggs JA
Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution
Nature (2015) 517:505-508. doi:10.1038/nature13838

2014

Bharat TA, Castillo Menendez LR, Hagen WJ, Lux V, Igonet S, Schorb M, Schur FKM, Kräusslich HG, Briggs JA.
Cryo-electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly
PNAS (2014) 111(22):8233-8238. doi: 10.1073/pnas.1401455111

2013

Schur FKM, Hagen WJ, de Marco A, Briggs JA.
Determination of protein structure at 8.5A resolution using cryo-electron tomography and sub-tomogram averaging
Journal of Structural Biology (2013) 184(3):394-400. doi: 10.1016/j.jsb.2013.10.015

Koestler SA, Steffen A, Nemethova M, Winterhoff M, Luo N, Holleboom JM, Krupp J, Jacob, S, Vinzenz M, Schur F, Schlüter K, Gunning PW, Winkler C, Schmeiser C, Faix J, Stradal TEB, Small JV, Rottner K.
Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin
Molecular Biology of the Cell (2013). 24, 2861-2875. doi: 10.1091/mbc.E12-12-0857

Steffen A, Ladwein M, Dimchev GA, Hein A, Schwenkmezger L, Arens S, Ladwein KI, Holleboom JM, Schur F, Small JV, Schwarz J, Gerhard R, Faix J, Stradal TEB, Brakebusch C, Rottner K
Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation
Journal of Cell Science (2013) 126, 4572-4588. doi: 10.1242/jcs.118232

2012

Vinzenz M, Nemethova M, Schur F, Mueller J, Narita A, Urban E, Winkler C, Schmeiser C, Koestler SA, Rottner K, Resch GP, Maeda Y, Small JV.
Actin branching in the initiation and maintenance of lamellipodia
Journal of Cell Science (2012). 125, 2775-85, doi:10.1242/jcs.107623

*equal contribution
# shared corresponding author